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This study in mice found that a heart rate reduction of 14% (induced by ivabradine) increased longevity by 6%. Comment: This is an animal study so applicability to humans is not certain. To what specific patient population would chemically inducing a slower heart rate be of benefit? Basic Res Cardiol. 2015 Mar;110(2):460.    (retrieved Jan, 2015). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.